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Index > Protein center > Avpr1a(Gene name) > Rat
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  • Avpr1a (Gene name),
  • Vasopressin V1a receptor (Protein name ),  V1AR_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Avpr1a;
    Protein name:
    Vasopressin V1a receptor(V1aR);
    Alternative:
    Antidiuretic hormone receptor 1a;AVPR V1a;Vascular/hepatic-type arginine vasopressin receptor;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cytoplasmic vesicle membrane Multi-pass membrane protein Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane.
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MSFPRGSQDR | SVGNSSPWWP | LTTEGSNGSQ | EAARLGEGDS | PLGDVRNEEL | 
    100:
    AKLEIAVLAV | IFVVAVLGNS | SVLLALHRTP | RKTSRMHLFI | RHLSLADLAV | 
    150:
    AFFQVLPQLC | WDITYRFRGP | DWLCRVVKHL | QVFAMFASAY | MLVVMTADRY | 
    200:
    IAVCHPLKTL | QQPARRSRLM | IATSWVLSFI | LSTPQYFIFS | VIEIEVNNGT | 
    250:
    KTQDCWATFI | QPWGTRAYVT | WMTSGVFVAP | VVVLGTCYGF | ICYHIWRNIR | 
    300:
    GKTASSRHSK | GDKGSGEAVG | PFHKGLLVTP | CVSSVKSISR | AKIRTVKMTF | 
    350:
    VIVSAYILCW | APFFIVQMWS | VWDENFIWTD | SENPSITITA | LLASLNSCCN | 
    400:
    PWIYMFFSGH | LLQDCVQSFP | CCHSMAQKFA | KDDSDSMSRR | QTSYSNNRSP | 
    424:
    TNSTGMWKDS | PKSSKSIRFI | PVST
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat V1aR
    Cat.:
    E9136r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat V1aR
    Cat.:
    E9136h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat V1aR
    Cat.:
    E9136m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat V1aR
    Cat.:
    U9136h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat V1aR
    Cat.:
    U9136r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat V1aR
    Cat.:
    U9136m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat V1aR
    Cat.:
    P9136Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat V1aR
    Polyclonal Antibody for Rat V1aR
    Cat.:
    P9136Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat V1aR
    Monoclonal Antibody for Rat V1aR
    Monoclonal Antibody for Rat V1aR
    Protein for Rat V1aR
    Protein for Rat V1aR
    Protein for Rat V1aR

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression of a rat V1a arginine vasopressin receptor."
      Morel A. , O'Carroll A.-M. , Brownstein M.J. , Lolait S.J.
      Nature356:523-526(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "Homology between neurohypophyseal hormone receptors."
      Wheatley M. , Howl J. , Morel A. , Davis A.R.L.
      Biochem. J.296:519-519(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 112-117
    3. 3.
      "Sequence identity between the rat and human vasopressin V1a receptors."
      Innamorati G. , Lolait S.J. , Birnbaumer M.
      Biochem. J.314:710-711(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Liver.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    5. 5.
      "Molecular cloning and expression of rat V1a and V2 arginine vasopressin receptors."
      Morel A. , Lolait S.J. , Brownstein M.J.
      Regul. Pept.45:53-59(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-395
    6. 6.
      "Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor."
      Chini B. , Mouillac B. , Ala Y. , Balestre M.-N. , Trumpp-Kallmeyer S. , Hoflack J. , Elands J. , Hibert M. , Manning M. , Jard S. , Barberis C.
      EMBO J.14:2176-2182(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TYR-115
    7. 7.
      "Localization of V1a vasopressin receptor mRNA expression in cultured neurons, astroglia, and oligodendroglia of rat cerebral cortex."
      Yamazaki R.S. , Chen Q. , Schreiber S.S. , Brinton R.D.
      Brain Res. Mol. Brain Res.45:138-140(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      "Effect of N-glycosylation on ligand binding affinity of rat V1a vasopressin receptor."
      Lee K.-H. , Ahn J. , Yu D.-H. , Jeong H.-S. , Lee S.-H. , Kim K.-S. , Chung I.-Y. , Kim J.-H. , Lee Y.-S.
      Biochem. Biophys. Res. Commun.286:707-713(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASN-14 AND ASN-27;SUBCELLULAR LOCATION
    9. 9.
      "Palmitoylation of the vasopressin V1a receptor reveals different conformational requirements for signaling, agonist-induced receptor phosphorylation, and sequestration."
      Hawtin S.R. , Tobin A.B. , Patel S. , Wheatley M.
      J. Biol. Chem.276:38139-38146(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-371 AND CYS-372;MUTAGENESIS OF CYS-371 AND CYS-372
    10. 10.
      "Immunocytochemical localization of vasopressin v1a receptors in the rat pituitary gonadotropes."
      Orcel H. , Tobin V.A. , Alonso G. , Rabie A.
      Endocrinology143:4385-4388(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 11.
      "Viral vector-mediated gene transfer of the vole V1a vasopressin receptor in the rat septum: improved social discrimination and active social behaviour."
      Landgraf R. , Frank E. , Aldag J.M. , Neumann I.D. , Sharer C.A. , Ren X. , Terwilliger E.F. , Niwa M. , Wigger A. , Young L.J.
      Eur. J. Neurosci.18:403-411(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN SOCIAL BEHAVIOR
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